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Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

FGF receptor 2 is involved in the formation of the neuromuscular junction (NMJ), but its in vivo ligand remains to be determined. Laser capture microdissection of the mouse spinal motor neurons (SMNs) revealed that Fgf18 mRNA is highly expressed in SMNs in adults. Expression of Fgf18 mRNA was the hi...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ito, Kenyu, Ohkawara, Bisei, Yagi, Hideki, Nakashima, Hiroaki, Tsushima, Mikito, Ota, Kyotaro, Konishi, Hiroyuki, Masuda, Akio, Imagama, Shiro, Kiyama, Hiroshi, Ishiguro, Naoki, Ohno, Kinji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765005/
https://ncbi.nlm.nih.gov/pubmed/29323161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18753-5
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