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Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

FGF receptor 2 is involved in the formation of the neuromuscular junction (NMJ), but its in vivo ligand remains to be determined. Laser capture microdissection of the mouse spinal motor neurons (SMNs) revealed that Fgf18 mRNA is highly expressed in SMNs in adults. Expression of Fgf18 mRNA was the hi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Ito, Kenyu, Ohkawara, Bisei, Yagi, Hideki, Nakashima, Hiroaki, Tsushima, Mikito, Ota, Kyotaro, Konishi, Hiroyuki, Masuda, Akio, Imagama, Shiro, Kiyama, Hiroshi, Ishiguro, Naoki, Ohno, Kinji
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765005/
https://ncbi.nlm.nih.gov/pubmed/29323161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18753-5
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