Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

FGF receptor 2 is involved in the formation of the neuromuscular junction (NMJ), but its in vivo ligand remains to be determined. Laser capture microdissection of the mouse spinal motor neurons (SMNs) revealed that Fgf18 mRNA is highly expressed in SMNs in adults. Expression of Fgf18 mRNA was the hi...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Ito, Kenyu, Ohkawara, Bisei, Yagi, Hideki, Nakashima, Hiroaki, Tsushima, Mikito, Ota, Kyotaro, Konishi, Hiroyuki, Masuda, Akio, Imagama, Shiro, Kiyama, Hiroshi, Ishiguro, Naoki, Ohno, Kinji
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765005/
https://ncbi.nlm.nih.gov/pubmed/29323161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18753-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items