MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice

In Huntington's disease (HD) patients and in model organisms, messenger RNA transcriptome has been extensively studied; in contrast, comparatively little is known about expression and potential role of microRNAs. Using RNA-sequencing, we have quantified microRNA expression in four brain regions...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Langfelder, Peter, Gao, Fuying, Wang, Nan, Howland, David, Kwak, Seung, Vogt, Thomas F., Aaronson, Jeffrey S., Rosinski, Jim, Coppola, Giovanni, Horvath, Steve, Yang, X. William
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764268/
https://ncbi.nlm.nih.gov/pubmed/29324753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190550
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