Gene Expression Analysis to Identify Mechanisms Underlying Heart Failure Susceptibility in Mice and Humans

BACKGROUND: Genetic factors are known to modulate cardiac susceptibility to ventricular hypertrophy and failure. To determine how strain influences the transcriptional response to pressure overload-induced heart failure (HF) and which of these changes accurately reflect the human disease, we analyze...

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Gepubliceerd in:Basic Res Cardiol
Hoofdauteurs: Koentges, Christoph, Pepin, Mark E., Müsse, Carolyn, Pfeil, Katharina, Viteri Alvarez, Sonia V., Hoppe, Natalie, Hoffmann, Michael M., Odening, Katja E., Sossalla, Samuel, Zirlik, Andreas, Hein, Lutz, Bode, Christoph, Wende, Adam R., Bugger, Heiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764079/
https://ncbi.nlm.nih.gov/pubmed/29288409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0666-6
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