Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate

The MKK1/2 kinase tumour progression locus 2 (TPL-2) is critical for the production of tumour necrosis factor alpha (TNFα) in innate immune responses and a potential anti-inflammatory drug target. Several earlier pharmaceutical company screens with the isolated TPL-2 kinase domain have identified sm...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Biochem J
Autores principales: Kümper, Sandra, Gantke, Thorsten, Chen, Chao-Sheng, Soneji, Yasmina, Pattison, Michael J., Chakravarty, Probir, Kjær, Svend, Thomas, Daniel, Haslam, Carl, Leavens, Bill J., House, David, Powell, David J., Ley, Steven C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763956/
https://ncbi.nlm.nih.gov/pubmed/29229763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170579
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares