TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis

Transforming growth factor β (TGF-β)/Smad3 signaling plays a role in tissue fibrosis. We report here that Erbb4-IR is a novel long non-coding RNA (lncRNA) responsible for TGF-β/Smad3-mediated renal fibrosis and is a specific therapeutic target for chronic kidney disease. Erbb4-IR was induced by TGF-...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Feng, Min, Tang, Patrick Ming-Kuen, Huang, Xiao-Ru, Sun, Si-Fan, You, Yong-Ke, Xiao, Jun, Lv, Lin-Li, Xu, An-Ping, Lan, Hui-Yao
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763082/
https://ncbi.nlm.nih.gov/pubmed/29102563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.09.024
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker