Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer

BACKGROUND AND AIMS: Docetaxel (DTX) modestly increases patient survival of metastatic castration-resistant prostate cancer (mCRPC) due to insurgence of pharmacological resistance. Deregulation of Chromosome Region Maintenance (CRM-1)/ exportin-1 (XPO-1)-mediated nuclear export may play a crucial ro...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Gravina, Giovanni Luca, Mancini, Andrea, Colapietro, Alessandro, Marampon, Francesco, Sferra, Roberta, Pompili, Simona, Biordi, Leda Assunta, Iorio, Roberto, Flati, Vincenzo, Argueta, Christian, Landesman, Yosef, Kauffman, Michael, Shacham, Sharon, Festuccia, Claudio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762317/
https://ncbi.nlm.nih.gov/pubmed/29340049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22760
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