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The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture

Production of most eukaryotic mRNAs requires splicing of introns from pre-mRNA. The splicing reaction requires definition of splice sites, which are initially recognized in either intron-spanning (‘intron definition’) or exon-spanning (‘exon definition’) pairs. To understand how exon and intron leng...

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Pubblicato in:eLife
Autori principali: Pai, Athma A, Henriques, Telmo, McCue, Kayla, Burkholder, Adam, Adelman, Karen, Burge, Christopher B
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762160/
https://ncbi.nlm.nih.gov/pubmed/29280736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32537
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