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Investigation of copper-free alkyne/azide 1,3-dipolar cycloadditions using microwave irradiation

The prevalence of 1,3-dipolar cycloadditions of azides and alkynes within both biology and chemistry highlights the utility of these reactions. However, the use of a copper catalyst can be prohibitive to some applications. Consequently, we have optimized a copper-free microwave assisted reaction to...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Chatkewitz, Lindsay E., Halonski, John F., Padilla, Marshall S., Young, Douglas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761740/
https://ncbi.nlm.nih.gov/pubmed/29248298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.12.007
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