T(3) and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice

Increasing brown adipose tissue (BAT) activity is regarded as a potential treatment of obese, hyperglycemic patients with metabolic syndrome. Triiodothyronine (T(3)) is known to stimulate BAT activity by increasing mitochondrial uncoupling protein 1 (Ucp1) gene transcription, leading to increased th...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Katz, Liora S., Xu, Shiliyang, Ge, Kai, Scott, Donald K., Gershengorn, Marvin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761585/
https://ncbi.nlm.nih.gov/pubmed/29077876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00579
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