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Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?

In a most simplified way, we can say that much of the symptomatology that characterizes Alzheimer's disease (AD) can be attributed to a cascade of toxic events initiated by the presence in the interstitial space of the brain of oligomers of the β‐amyloid peptide (Aβ) peptide, a cleavage by‐prod...

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Bibliografske podrobnosti
izdano v:EMBO Mol Med
Main Authors: Guix, Francesc X, Dotti, Carlos G
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760883/
https://ncbi.nlm.nih.gov/pubmed/29208637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708491
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