Membrane Incorporation, Channel Formation, and Disruption of Calcium Homeostasis by Alzheimer's β-Amyloid Protein

Oligomerization, conformational changes, and the consequent neurodegeneration of Alzheimer's β-amyloid protein (AβP) play crucial roles in the pathogenesis of Alzheimer's disease (AD). Mounting evidence suggests that oligomeric AβPs cause the disruption of calcium homeostasis, eventually l...

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Main Authors: Kawahara, Masahiro, Ohtsuka, Isao, Yokoyama, Shoko, Kato-Negishi, Midori, Sadakane, Yutaka
格式: Artigo
語言:Inglês
出版: SAGE-Hindawi Access to Research 2011
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Review Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087492/
https://ncbi.nlm.nih.gov/pubmed/21547225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/304583
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