Punctuated evolution of canonical genomic aberrations in uveal melanoma

Cancer is thought to arise through the accumulation of genomic aberrations evolving under Darwinian selection. However, it remains unclear when the aberrations associated with metastasis emerge during tumor evolution. Uveal melanoma (UM) is the most common primary eye cancer and frequently leads to...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Field, Matthew G., Durante, Michael A., Anbunathan, Hima, Cai, Louis Z., Decatur, Christina L., Bowcock, Anne M., Kurtenbach, Stefan, Harbour, J. William
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760704/
https://ncbi.nlm.nih.gov/pubmed/29317634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02428-w
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