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Punctuated evolution of canonical genomic aberrations in uveal melanoma

Cancer is thought to arise through the accumulation of genomic aberrations evolving under Darwinian selection. However, it remains unclear when the aberrations associated with metastasis emerge during tumor evolution. Uveal melanoma (UM) is the most common primary eye cancer and frequently leads to...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Field, Matthew G., Durante, Michael A., Anbunathan, Hima, Cai, Louis Z., Decatur, Christina L., Bowcock, Anne M., Kurtenbach, Stefan, Harbour, J. William
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760704/
https://ncbi.nlm.nih.gov/pubmed/29317634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02428-w
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