Driver Mutations in Uveal Melanoma: Associations With Gene Expression Profile and Patient Outcomes

IMPORTANCE: Frequent mutations have been described in the following 5 genes in uveal melanoma (UM): BAP1, EIF1AX, GNA11, GNAQ, and SF3B1. Understanding the prognostic significance of these mutations could facilitate their use in precision medicine. OBJECTIVE: To determine the associations between dr...

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Veröffentlicht in:JAMA Ophthalmol
Hauptverfasser: Decatur, Christina L., Ong, Erin, Garg, Nisha, Anbunathan, Hima, Bowcock, Anne M., Field, Matthew G., Harbour, J. William
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966162/
https://ncbi.nlm.nih.gov/pubmed/27123562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2016.0903
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