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GNAQ/11 Mutations in Uveal Melanoma: Is YAP the Key to Targeted Therapy?
GNAQ and GNA11 are frequently mutated in uveal melanoma, but they remain difficult therapeutic targets. In this issue of Cancer Cell, Feng and colleagues and Yu and colleagues demonstrate that the oncogenic activity of mutant GNAQ/11 is mediated at least in part through YAP, potentially uncovering a...
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| 出版年: | Cancer Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966161/ https://ncbi.nlm.nih.gov/pubmed/24937456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.05.028 |
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