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GNAQ/11 Mutations in Uveal Melanoma: Is YAP the Key to Targeted Therapy?
GNAQ and GNA11 are frequently mutated in uveal melanoma, but they remain difficult therapeutic targets. In this issue of Cancer Cell, Feng and colleagues and Yu and colleagues demonstrate that the oncogenic activity of mutant GNAQ/11 is mediated at least in part through YAP, potentially uncovering a...
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| Publicat a: | Cancer Cell |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966161/ https://ncbi.nlm.nih.gov/pubmed/24937456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.05.028 |
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