Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion

Zika virus (ZIKV) infection is a public health emergency and host innate immunity is essential for the control of virus infection. The NLRP3 inflammasome plays a key role in host innate immune responses by activating caspase-1 to facilitate interleukin-1β (IL-1β) secretion. Here we report that ZIKV...

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Pubblicato in:Nat Commun
Autori principali: Wang, Wenbiao, Li, Geng, De Wu, Luo, Zhen, Pan, Pan, Tian, Mingfu, Wang, Yingchong, Xiao, Feng, Li, Aixin, Wu, Kailang, Liu, Xiaohong, Rao, Lang, Liu, Fang, Liu, Yingle, Wu, Jianguo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760693/
https://ncbi.nlm.nih.gov/pubmed/29317641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02645-3
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