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STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection

One of the fundamental reactions of the innate immune responses to pathogen infection is the release of pro-inflammatory cytokines, including IL-1β, processed by the NLRP3 inflammasome. The stimulator of interferon genes (STING) has the essential roles in innate immune response against pathogen infe...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Wang, Wenbiao, Hu, Dingwen, Wu, Caifeng, Feng, Yuqian, Li, Aixin, Liu, Weiyong, Wang, Yingchong, Chen, Keli, Tian, Mingfu, Xiao, Feng, Zhang, Qi, Shereen, Muhammad Adnan, Chen, Weijie, Pan, Pan, Wan, Pin, Wu, Kailang, Wu, Jianguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080238/
https://ncbi.nlm.nih.gov/pubmed/32187211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008335
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