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EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex
Activation of NLRP3 inflammasome is important for effective host defense against invading pathogen. Together with apoptosis-associated speck-like protein containing CARD domain (ASC), NLRP3 induces the cleavage of caspase-1 to facilitate the maturation of interleukin-1beta (IL-1β), an important pro-...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5245909/ https://ncbi.nlm.nih.gov/pubmed/28060938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006123 |
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