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EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex

Activation of NLRP3 inflammasome is important for effective host defense against invading pathogen. Together with apoptosis-associated speck-like protein containing CARD domain (ASC), NLRP3 induces the cleavage of caspase-1 to facilitate the maturation of interleukin-1beta (IL-1β), an important pro-...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Wang, Wenbiao, Xiao, Feng, Wan, Pin, Pan, Pan, Zhang, Yecheng, Liu, Fang, Wu, Kailang, Liu, Yingle, Wu, Jianguo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245909/
https://ncbi.nlm.nih.gov/pubmed/28060938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006123
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