EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex

Activation of NLRP3 inflammasome is important for effective host defense against invading pathogen. Together with apoptosis-associated speck-like protein containing CARD domain (ASC), NLRP3 induces the cleavage of caspase-1 to facilitate the maturation of interleukin-1beta (IL-1β), an important pro-...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Wang, Wenbiao, Xiao, Feng, Wan, Pin, Pan, Pan, Zhang, Yecheng, Liu, Fang, Wu, Kailang, Liu, Yingle, Wu, Jianguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245909/
https://ncbi.nlm.nih.gov/pubmed/28060938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006123
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