Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally

DNA methylation is an epigenetic modification of the genome involved in regulating crucial cellular processes, including transcription and chromosome stability. Advances in PacBio sequencing technologies can be used to robustly reveal methylation sites. The methylome of the Mycobacterium tuberculosi...

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Publicat a:Sci Rep
Autors principals: Phelan, Jody, de Sessions, Paola Florez, Tientcheu, Leopold, Perdigao, Joao, Machado, Diana, Hasan, Rumina, Hasan, Zahra, Bergval, Indra L., Anthony, Richard, McNerney, Ruth, Antonio, Martin, Portugal, Isabel, Viveiros, Miguel, Campino, Susana, Hibberd, Martin L., Clark, Taane G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760664/
https://ncbi.nlm.nih.gov/pubmed/29317751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18188-y
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