Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally

DNA methylation is an epigenetic modification of the genome involved in regulating crucial cellular processes, including transcription and chromosome stability. Advances in PacBio sequencing technologies can be used to robustly reveal methylation sites. The methylome of the Mycobacterium tuberculosi...

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Publicado en:Sci Rep
Autores principales: Phelan, Jody, de Sessions, Paola Florez, Tientcheu, Leopold, Perdigao, Joao, Machado, Diana, Hasan, Rumina, Hasan, Zahra, Bergval, Indra L., Anthony, Richard, McNerney, Ruth, Antonio, Martin, Portugal, Isabel, Viveiros, Miguel, Campino, Susana, Hibberd, Martin L., Clark, Taane G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760664/
https://ncbi.nlm.nih.gov/pubmed/29317751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18188-y
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