Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance

BACKGROUND: Continuing evolution of the Mycobacterium tuberculosis (Mtb) complex genomes associated with resistance to anti-tuberculosis drugs is threatening tuberculosis disease control efforts. Both multi- and extensively drug resistant Mtb (MDR and XDR, respectively) are increasing in prevalence,...

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Publicat a:BMC Genomics
Autors principals: Oppong, Yaa E. A., Phelan, Jody, Perdigão, João, Machado, Diana, Miranda, Anabela, Portugal, Isabel, Viveiros, Miguel, Clark, Taane G., Hibberd, Martin L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440112/
https://ncbi.nlm.nih.gov/pubmed/30922221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5615-3
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