RNA elongation by respiratory syncytial virus polymerase is calibrated by conserved region V

The large polymerase subunit (L) of non-segmented negative strand RNA viruses transcribes viral mRNAs and replicates the viral genome. Studies with VSV have shown that conserved region V (CRV) of the L protein is part of the capping domain. However, CRV folds over and protrudes into the polymerizati...

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Vydáno v:PLoS Pathog
Hlavní autoři: Braun, Molly R., Deflubé, Laure R., Noton, Sarah L., Mawhorter, Michael E., Tremaglio, Chadene Z., Fearns, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760109/
https://ncbi.nlm.nih.gov/pubmed/29281742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006803
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