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The Respiratory Syncytial Virus Polymerase Has Multiple RNA Synthesis Activities at the Promoter

Respiratory syncytial virus (RSV) is an RNA virus in the Family Paramyxoviridae. Here, the activities performed by the RSV polymerase when it encounters the viral antigenomic promoter were examined. RSV RNA synthesis was reconstituted in vitro using recombinant, isolated polymerase and an RNA oligon...

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Detalhes bibliográficos
Main Authors: Noton, Sarah L., Deflubé, Laure R., Tremaglio, Chadene Z., Fearns, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475672/
https://ncbi.nlm.nih.gov/pubmed/23093940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002980
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