FACTORS AFFECTING DE NOVO RNA SYNTHESIS AND BACK-PRIMING BY THE RESPIRATORY SYNCYTIAL VIRUS POLYMERASE

Respiratory syncytial virus RNA dependent RNA polymerase (RdRp) initiates RNA synthesis from the leader (le) and trailer-complement (trc) promoters. The RdRp can also add nucleotides to the 3′ end of the trc promoter by back-priming, but there is no evidence this occurs at the le promoter in infecte...

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Hlavní autoři: Noton, Sarah L., Aljabr, Waleed, Hiscox, Julian A., Matthews, David A., Fearns, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125506/
https://ncbi.nlm.nih.gov/pubmed/25010481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.05.032
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