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Respiratory Syncytial Virus Inhibitor AZ-27 Differentially Inhibits Different Polymerase Activities at the Promoter

Respiratory syncytial virus (RSV) is the leading cause of pediatric respiratory disease. RSV has an RNA-dependent RNA polymerase that transcribes and replicates the viral negative-sense RNA genome. The large polymerase subunit (L) has multiple enzymatic activities, having the capability to synthesiz...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Noton, Sarah L., Nagendra, Kartikeya, Dunn, Ewan F., Mawhorter, Michael E., Yu, Qin, Fearns, Rachel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505683/
https://ncbi.nlm.nih.gov/pubmed/25995255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00530-15
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