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The human papillomavirus DNA helicase E1 binds, stimulates, and confers processivity to cellular DNA polymerase epsilon

The papillomavirus (PV) helicase protein E1 recruits components of the cellular DNA replication machinery to the PV replication fork, such as Replication Protein A (RPA), DNA polymerase α-primase (pol α) and topoisomerase I (topo I). Here we show that E1 binds to DNA polymerase ϵ (pol ϵ) and dramati...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Chojnacki, Michaelle, Melendy, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758917/
https://ncbi.nlm.nih.gov/pubmed/29155954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1103
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