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The human papillomavirus DNA helicase E1 binds, stimulates, and confers processivity to cellular DNA polymerase epsilon

The papillomavirus (PV) helicase protein E1 recruits components of the cellular DNA replication machinery to the PV replication fork, such as Replication Protein A (RPA), DNA polymerase α-primase (pol α) and topoisomerase I (topo I). Here we show that E1 binds to DNA polymerase ϵ (pol ϵ) and dramati...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Chojnacki, Michaelle, Melendy, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758917/
https://ncbi.nlm.nih.gov/pubmed/29155954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1103
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