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An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase

Helicases couple ATP hydrolysis to nucleic acid binding and unwinding via molecular mechanisms that remain poorly defined for most enzyme subfamilies within the superfamily 2 (SF2) helicase group. A crystal structure of the PriA SF2 DNA helicase, which governs restart of prematurely terminated repli...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Windgassen, Tricia A., Keck, James L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175346/
https://ncbi.nlm.nih.gov/pubmed/27484483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw690
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