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An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase
Helicases couple ATP hydrolysis to nucleic acid binding and unwinding via molecular mechanisms that remain poorly defined for most enzyme subfamilies within the superfamily 2 (SF2) helicase group. A crystal structure of the PriA SF2 DNA helicase, which governs restart of prematurely terminated repli...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175346/ https://ncbi.nlm.nih.gov/pubmed/27484483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw690 |
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