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Function of a strand-separation pin element in the PriA DNA replication restart helicase

DNA helicases are motor proteins that couple the chemical energy of nucleoside triphosphate hydrolysis to the mechanical functions required for DNA unwinding. Studies of several helicases have identified strand-separating “pin” structures that are positioned to intercept incoming dsDNA and promote s...

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Pubblicato in:J Biol Chem
Autori principali: Windgassen, Tricia A., Leroux, Maxime, Sandler, Steven J., Keck, James L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393597/
https://ncbi.nlm.nih.gov/pubmed/30593500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006870
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