Integrating sequence and gene expression information predicts genome-wide DNA-binding proteins and suggests a cooperative mechanism

DNA-binding proteins (DBPs) perform diverse biological functions ranging from transcription to pathogen sensing. Machine learning methods can not only identify DBPs de novo but also provide insights into their DNA-recognition dynamics. However, it remains unclear whether available methods that can a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ahmad, Shandar, Prathipati, Philip, Tripathi, Lokesh P, Chen, Yi-An, Arya, Ajay, Murakami, Yoichi, Mizuguchi, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758906/
https://ncbi.nlm.nih.gov/pubmed/29186632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1166
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