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Predicting conformational ensembles and genome-wide transcription factor binding sites from DNA sequences
DNA shape is emerging as an important determinant of transcription factor binding beyond just the DNA sequence. The only tool for large scale DNA shape estimates, DNAshape was derived from Monte-Carlo simulations and predicts four broad and static DNA shape features, Propeller twist, Helical twist,...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5481346/ https://ncbi.nlm.nih.gov/pubmed/28642456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03199-6 |
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