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A novel and quick PCR-based method to genotype mice with a leptin receptor mutation (db/db mice)
db/db mice is one of most widely used animal models in studying the cellular and molecular mechanisms of metabolic disorders, such as diabetes, hyperlipidemia, and obesity. The mice carry spontaneous point mutations in the gene encoding the leptin receptor, leading to leptin receptor inactivation. S...
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| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758667/ https://ncbi.nlm.nih.gov/pubmed/28748911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.52 |
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