MG53 Does Not Manifest the Development of Diabetes in db/db Mice

MG53 is a member of the TRIM protein family that is predominantly expressed in striated muscles and participates in cell membrane repair. Controversy exists regarding MG53’s role in insulin signaling and manifestation of diabetes. We generated db/db mice with either whole-body ablation or sustained...

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Vydáno v:Diabetes
Hlavní autoři: Wang, Qiang, Bian, Zehua, Jiang, Qiwei, Wang, Xiaoliang, Zhou, Xinyu, Park, Ki Ho, Hsueh, Willa, Whitson, Bryan A., Haggard, Erin, Li, Haichang, Chen, Ken, Cai, Chuanxi, Tan, Tao, Zhu, Hua, Ma, Jianjie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2020
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171965/
https://ncbi.nlm.nih.gov/pubmed/32139593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0807
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