MG53 Does Not Manifest the Development of Diabetes in db/db Mice

MG53 is a member of the TRIM protein family that is predominantly expressed in striated muscles and participates in cell membrane repair. Controversy exists regarding MG53’s role in insulin signaling and manifestation of diabetes. We generated db/db mice with either whole-body ablation or sustained...

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Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Wang, Qiang, Bian, Zehua, Jiang, Qiwei, Wang, Xiaoliang, Zhou, Xinyu, Park, Ki Ho, Hsueh, Willa, Whitson, Bryan A., Haggard, Erin, Li, Haichang, Chen, Ken, Cai, Chuanxi, Tan, Tao, Zhu, Hua, Ma, Jianjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2020
Soggetti:
Pharmacology and Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171965/
https://ncbi.nlm.nih.gov/pubmed/32139593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0807
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