MG53 Does Not Manifest the Development of Diabetes in db/db Mice

MG53 is a member of the TRIM protein family that is predominantly expressed in striated muscles and participates in cell membrane repair. Controversy exists regarding MG53’s role in insulin signaling and manifestation of diabetes. We generated db/db mice with either whole-body ablation or sustained...

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Bibliographic Details
Published in:Diabetes
Main Authors: Wang, Qiang, Bian, Zehua, Jiang, Qiwei, Wang, Xiaoliang, Zhou, Xinyu, Park, Ki Ho, Hsueh, Willa, Whitson, Bryan A., Haggard, Erin, Li, Haichang, Chen, Ken, Cai, Chuanxi, Tan, Tao, Zhu, Hua, Ma, Jianjie
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2020
Subjects:
Pharmacology and Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171965/
https://ncbi.nlm.nih.gov/pubmed/32139593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0807
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