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A novel and quick PCR-based method to genotype mice with a leptin receptor mutation (db/db mice)
db/db mice is one of most widely used animal models in studying the cellular and molecular mechanisms of metabolic disorders, such as diabetes, hyperlipidemia, and obesity. The mice carry spontaneous point mutations in the gene encoding the leptin receptor, leading to leptin receptor inactivation. S...
Enregistré dans:
| Publié dans: | Acta Pharmacol Sin |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758667/ https://ncbi.nlm.nih.gov/pubmed/28748911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.52 |
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