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A novel and quick PCR-based method to genotype mice with a leptin receptor mutation (db/db mice)
db/db mice is one of most widely used animal models in studying the cellular and molecular mechanisms of metabolic disorders, such as diabetes, hyperlipidemia, and obesity. The mice carry spontaneous point mutations in the gene encoding the leptin receptor, leading to leptin receptor inactivation. S...
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| Publicat a: | Acta Pharmacol Sin |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758667/ https://ncbi.nlm.nih.gov/pubmed/28748911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.52 |
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