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Differences in metabolomic profiles of male db/db and s/s, leptin receptor mutant mice
Leptin, a protein hormone secreted by adipose tissue, plays an important role in regulating energy metabolism and the immune response. Despite similar extremes of adiposity, mutant mouse models, db/db, carrying spontaneous deletion of the active form of the leptin receptor (LEPR-B) intracellular sig...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073954/ https://ncbi.nlm.nih.gov/pubmed/22318992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00081.2011 |
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