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Differences in metabolomic profiles of male db/db and s/s, leptin receptor mutant mice

Leptin, a protein hormone secreted by adipose tissue, plays an important role in regulating energy metabolism and the immune response. Despite similar extremes of adiposity, mutant mouse models, db/db, carrying spontaneous deletion of the active form of the leptin receptor (LEPR-B) intracellular sig...

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Autores principales: Saadat, Nadia, IglayReger, Heidi B., Myers, Martin G., Bodary, Peter, Gupta, Smiti V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073954/
https://ncbi.nlm.nih.gov/pubmed/22318992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00081.2011
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