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Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPARγ
Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the nuclear receptor superfamily. It functions as a ligand-activated transcription factor and plays important roles in the regulation of adipocyte differentiation, insulin resistance, and inflammation. Here, we report the crystal st...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758645/ https://ncbi.nlm.nih.gov/pubmed/29311579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18274-1 |
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