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Differential Effects of Cancer-Associated Mutations Enriched in Helix H3 of PPARγ
SIMPLE SUMMARY: The high frequency of mutations in helix H3 of the peroxisome proliferator-activated receptor gamma (PPARγ) ligand-binding domain (LBD) in various cancers suggest that this region has an important role in tumorigenesis. In this study, we performed bioinformatics, structural and bioch...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7761077/ https://ncbi.nlm.nih.gov/pubmed/33266062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123580 |
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