Smad3‐mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial–mesenchymal transition

During epithelial–mesenchymal transition (EMT), reprogramming of gene expression is accompanied by histone modifications. Whether EMT‐promoting signaling directs functional changes in histone methylation has not been established. We show here that the histone lysine methyltransferase SETDB1 represse...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Du, Dan, Katsuno, Yoko, Meyer, Dominique, Budi, Erine H, Chen, Si‐Han, Koeppen, Hartmut, Wang, Hongjun, Akhurst, Rosemary J, Derynck, Rik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757214/
https://ncbi.nlm.nih.gov/pubmed/29233829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744250
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