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Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer
E3 ubiquitin (UB) ligases E4B and carboxyl terminus of Hsc70-interacting protein (CHIP) use a common U-box motif to transfer UB from E1 and E2 enzymes to their substrate proteins and regulate diverse cellular processes. To profile their ubiquitination targets in the cell, we used phage display to en...
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| Published in: | Sci Adv |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Association for the Advancement of Science
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5756662/ https://ncbi.nlm.nih.gov/pubmed/29326975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1701393 |
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