Metformin enhances the chemosensitivity of hepatocarcinoma cells to cisplatin through AMPK pathway

This study investigated the effect of metformin on chemosensitivity of hepatocarcinoma cells to cisplatin and the possible mechanism. HepG2 and Huh-7 hepatoma cells were treated with cisplatin at concentrations of 0, 2, 4, 6, 8 and 10 µM for 48 h. Proliferation of HepG2 and Huh-7 hepatoma cells were...

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Vydáno v:Oncol Lett
Hlavní autoři: Dong, Hao, Huang, Jungang, Zheng, Kang, Tan, Dong, Chang, Qi, Gong, Genqiang, Zhang, Qing, Tang, Hanqiu, Sun, Jianguo, Zhang, Shaoyu
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755027/
https://ncbi.nlm.nih.gov/pubmed/29344225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7198
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