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Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Cisplatin is currently used to treat inoperable recurrent meningiomas, but its side effects and drug resistance limit its use. Metformin has recently been identified as a chemosensitizing agent. However, the combined treatment of cisplatin and metformin in high-grade meningiomas has not been reporte...
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| Publicado en: | Mol Ther Oncolytics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7851485/ https://ncbi.nlm.nih.gov/pubmed/33575476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.11.004 |
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