Metformin enhances the chemosensitivity of hepatocarcinoma cells to cisplatin through AMPK pathway

This study investigated the effect of metformin on chemosensitivity of hepatocarcinoma cells to cisplatin and the possible mechanism. HepG2 and Huh-7 hepatoma cells were treated with cisplatin at concentrations of 0, 2, 4, 6, 8 and 10 µM for 48 h. Proliferation of HepG2 and Huh-7 hepatoma cells were...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Dong, Hao, Huang, Jungang, Zheng, Kang, Tan, Dong, Chang, Qi, Gong, Genqiang, Zhang, Qing, Tang, Hanqiu, Sun, Jianguo, Zhang, Shaoyu
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755027/
https://ncbi.nlm.nih.gov/pubmed/29344225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7198
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