Metformin and berberine synergistically improve NAFLD via the AMPK–SREBP1–FASN signaling pathway

Abstract Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic condition linked to dyslipidemia, insulin resistance, and persistent inflammation. Due to its complex pathogenesis, no approved pharmacological treatments currently exist. The research sought to explore the combined impact of...

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Detalhes bibliográficos

Principais autores:	Na Li, Quan-wei Chen, Xiao-long Gong, Fang Liu, Bin Zhang, Qi-shen Wang, Hao Zhang, Jian-jun Han
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-08-01
coleção:	Scientific Reports
Assuntos:	NAFLD Metformin Berberine AMPK signaling Synergistic therapy
Acesso em linha:	https://doi.org/10.1038/s41598-025-15495-7
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