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UVB radiation represses CYLD expression in melanocytes

CYLD lysine 63 deubiquitinase (CYLD) was originally identified as a tumor suppressor that is mutated in familial cylindromatosis. Unlike in cylindromatosis, downregulation of the deubiquitinase CYLD in melanoma, a highly aggressive tumor, is not caused by mutations in the CYLD gene, but rather by a...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Kuphal, Silke, Schneider, Nadja, Massoumi, Ramin, Hellerbrand, Claus, Bosserhoff, Anja Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754916/
https://ncbi.nlm.nih.gov/pubmed/29344161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7120
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