HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth

In addition to genetic changes, post-transcriptional events strongly contribute to the progression of malignant tumors. The RNA-binding protein HuR (<i>ELAVL1</i>) is able to bind and stabilize a large group of target mRNAs, which contain AU-rich elements (ARE) in their 3′-untranslated r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Janika K. Liebig, Silke Kuphal, Anja Katrin Bosserhoff
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-05-01
Colecção:Cancers
Assuntos:
malignant melanoma
HuR
oncogene induced senescence
MITF
Microphthalmia-associated transcription factor
Acesso em linha:https://www.mdpi.com/2072-6694/12/5/1299
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados