HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth

In addition to genetic changes, post-transcriptional events strongly contribute to the progression of malignant tumors. The RNA-binding protein HuR (<i>ELAVL1</i>) is able to bind and stabilize a large group of target mRNAs, which contain AU-rich elements (ARE) in their 3′-untranslated r...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Janika K. Liebig, Silke Kuphal, Anja Katrin Bosserhoff
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-05-01
Seri Bilgileri:Cancers
Konular:
malignant melanoma
HuR
oncogene induced senescence
MITF
Microphthalmia-associated transcription factor
Online Erişim:https://www.mdpi.com/2072-6694/12/5/1299
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller