A carregar...
Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors
Histone deacetylases (HDACs) regulate myriad cellular processes by catalyzing the hydrolysis of acetyl–l-lysine residues in histone and nonhistone proteins. The Zn(2+)-dependent class IIb enzyme HDAC6 regulates microtubule function by deacetylating α-tubulin, which suppresses microtubule dynamics an...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5754815/ https://ncbi.nlm.nih.gov/pubmed/29203661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718823114 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|