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Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy
Mitochondrial dysfunction manifests as different neurological diseases, but the mechanisms underlying the clinical variability remain poorly understood. To clarify whether different brain cells have differential sensitivity to mitochondrial dysfunction, we induced mitochondrial DNA (mtDNA) depletion...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5754366/ https://ncbi.nlm.nih.gov/pubmed/29302033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01859-9 |
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